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31. That could be a big deal: U. S. sales of cholesterol-lowering drugs — which include Merck's Zocor and Pfizer's Lipitor, among others — topped $20 billion last year, according to IMS Health.
32. Chevy's makes a big deal out of the "fresh" in its name and with good reason including: no cans in the restaurant, fresh salsa blended every hour, and fresh avocados smashed daily for guacamole.
33. Man B: Don't make such a big deal, it's only an earring.
34. This is not a big deal because when you use an untyped DataSet you would still likely have to change some client code if the underlying schema changes.
35. Fleas will only cause mild itchiness on cat's skin. Its nature's rule, not a big deal!
36. Finding terbium and dysprosium is a big deal. It will increase supply for most applications.
37. As to the actual substance of their graduate studies, it's not a big deal for them, as long as it leads to that degree or diploma.
38. Cheval 's former boss, Bradley Rotter, knew the offer was a big deal: "Dennis had already been managing money for me, and I did very well."
39. Make a big deal out of them. If you don't, no one will.
40. "The frequency of the physical activity is a big deal here[sentencedict.com], " says Nieman. "You can't be a weekend warrior and expect these effects."
41. The palmer accompanies him on all of his adventures but this one, and Spenser in stanza two of this canto makes a big deal of the fact that Guyon is descending in to the Cave of Mammon by himself.
42. Do you make a big deal out of unimportant issues?
43. Note passing a quick reprimand, so don't make a big deal out of it.
44. Kristen tries to be a strong independent female and always makes a big deal out of going out with her girlfriends on V-Day.
45. ForIndians even a kissing scene from a movie is a big deal and that is quite odd,especially since the country invented Kama Sutra.
46. Indeed, Mr. Obama has lately been going where the money isn't, making a big deal out of a freeze on nonsecurity discretionary spending[http://Sentencedict.com], which accounts for only 12 percent of the budget.
47. "It's a big deal every time, because it's really one of the most sensitive indicators," said Cummins Catherwood, managing director at Boenning and Scattergood in West Conshohocken, Pennsylvania.
48. Accommodating a Pregnancy Xiaomin never thought abortion was a big deal.
49. For example, being stuck in traffic on your way to work is a stressor. But traffic on a leisurely Sunday isn't a big deal.
50. And given Apple's influence, how Apple chooses to make that software do the digital cha-cha is a big deal.
51. Ducking altar boy practice was a big deal to someone who hung a crucifix on the wall, prayed the rosary, and considered Father James Cronin, the longtime pastor of my church, a saint.
52. Oh, it's not a big deal. Just a paper jam. I'll take them out.
53. A big deal like that would need approval from China's highest administrative body, the State Council.
54. Ten years ago, a computer with a built-in CD burner was a big deal. Owners could be sure to broaden their circle of friends and music collection.
55. Our culture tells us not to make a big deal out of rejection: "Don't be a whiner.